Resolution better than PET

The images produced by the Lowrad 10 have a spatial resolution approaching 2mm. This is better than state of the art PET imaging and is a significant improvement over the 10-12mm resolution associated with SPECT or traditional gamma camera planar imaging. The exact spatial resolution achievable with the Lowrad 10 depends on the resolution of the gamma camera it is being used with.

We show below an example of the resolution that can be achieved using the Lowrad 10. Figures 1 and 2 below show 4 glass hollow tubes of internal diameter 0.4mm, placed to form a rectangular cross with ends separated by 8mm and filled with technetium-99. Figure 1 is the image produced with a high quality collimated gamma camera. Figure 2 is the image produced with the Lowrad 10 in place of the collimator (on the same camera).

Traditional Gamma camera output

Figure 1: Traditional Gamma camera output

Lowrad 10 output

Figure 2: Lowrad 10 output

As you can see from the figures above the 8mm gap between the tubes is clearly visible on the Lowrad 10 output, but totally invisible when the traditional collimators are used.

Comparison of common nuclear imaging modalities
Planar SPECT PET Lowrad
Imaging type 2D 3D 3D 3D
Resolution 10-12mm 8-15mm 3-4mm 2-3mm
Isotopes Tc99, I123, Th201 Tc99, I123, Th201 FDG18, C11, O15, N13 Tc99, I123, Th201